【解决方案】马尔文帕纳科为药物挑选按下快进键！

版块：机械制造类型：普通作者：化工产业技术分享查看：212 回复：0 获赞：0 时间：2022-05-20 17:03:34

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马尔文帕纳科为药物挑选按下快进键！

使用生物物理片段挑选“甜美点”

发现按捺BRPF1 的新化学型

马尔文帕纳科为药物挑选按下快进键！

根据化合物库的有用采样是片段挑选射中 (fragment screening hit) 辨认范式的中心。一般片段分子越小，采样功率越高。关于小分子和靶蛋白之间弱结合力的检测才能决议了片段分子能够规划的巨细。

CLS共同的片段挑选渠道

马尔文帕纳科旗下Concept Life Sciences和TEC传感器 | 猫掌外链

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box-sizing: border-box; overflow-wrap: break-word !important; font-size: 18px; color: rgb(0, 98, 113); text-align: justify; visibility: visible;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; clear: both; min-height: 1em; white-space: normal; visibility: visible; overflow-wrap: break-word !important;"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; visibility: visible;">使用生物物理片段挑选“甜美点”</strong></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; clear: both; min-height: 1em; white-space: normal; visibility: visible; overflow-wrap: break-word !important;"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; visibility: visible;">发现按捺BRPF1 的新化学型</strong></p></section></section><section powered-by="xiumi.us" style="margin: 0px; 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box-sizing: border-box; color: rgb(0, 173, 80); visibility: visible; overflow-wrap: break-word !important;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; clear: both; min-height: 1em; white-space: normal; visibility: visible; overflow-wrap: break-word !important;"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; visibility: visible;">马尔文帕纳科为药物挑选按下快进键！</strong></p></section></section><section powered-by="xiumi.us" style="margin: 17px 0px 35px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; visibility: visible;"><section style="margin: 0px; padding: 0px 18px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; color: rgb(62, 62, 62); line-height: 1.8; letter-spacing: 1px; font-family: Optima-Regular, PingFangTC-light; visibility: visible;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; clear: both; min-height: 1em; text-indent: 2em; white-space: normal; visibility: visible; overflow-wrap: break-word !important;"></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; clear: both; min-height: 1em; text-indent: 2em; white-space: normal; visibility: visible; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; text-indent: 2em; visibility: visible;">根据化合物库的有用采样是片段挑选射中 (fragment screening hit) 辨认范式的中心。一般片段分子越小，采样功率越高。关于小分子和靶蛋白之间弱结合力的检测才能决议了片段分子能够规划的巨细。</span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; clear: both; min-height: 1em; text-indent: 2em; white-space: normal; visibility: visible; overflow-wrap: break-word !important;"><span style="margin: 0px; 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outline: 0px; max-width: 100%; box-sizing: border-box !important; overflow-wrap: break-word !important; visibility: visible;"><svg viewbox="" style="float: left; line-height: 0; width: 0px; vertical-align: top; visibility: visible;"></svg></section></section></section></section></section><section style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; display: inline-block; vertical-align: middle; width: auto; align-self: center; min-width: 10%; flex: 0 0 auto; height: auto; visibility: visible;"><section powered-by="xiumi.us" style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; justify-content: flex-start; visibility: visible;"><section style="margin: 0px; padding: 0px 13px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; font-size: 20px; text-align: center; color: rgb(0, 98, 113); line-height: 1; visibility: visible;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; clear: both; min-height: 1em; visibility: visible; overflow-wrap: break-word !important;"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; visibility: visible;">CLS共同的片段挑选渠道</strong></p></section></section></section></section></section><section powered-by="xiumi.us" style="margin: 17px 0px 35px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; visibility: visible;"><section style="margin: 0px; padding: 0px 18px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; color: rgb(62, 62, 62); line-height: 1.8; letter-spacing: 1px; font-family: Optima-Regular, PingFangTC-light; visibility: visible;"><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; clear: both; min-height: 1em; text-indent: 2em; white-space: normal; visibility: visible; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; text-indent: 2em; visibility: visible;"><br style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; visibility: visible;" /></span></p><p style="margin-top: 0px; margin-bottom: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; clear: both; min-height: 1em; text-indent: 2em; white-space: normal; visibility: visible; overflow-wrap: break-word !important;"><strong style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important;">马尔文帕纳科旗下<span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; text-indent: 2em; color: rgb(206, 0, 88);"><em style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important; text-indent: 2em; color: rgb(62, 62, 62);">Concept Life Sciences</span></em></span>和<em style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; overflow-wrap: break-word !important;"><span style="margin: 0px; padding: 0px; outline: 0px; max-width: 100%; box-sizing: border-box; text-indent: 2em; overfl

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